Mushroom Toxicity

Dogs and cats are curious creatures. When outside, they wander around with their noses to the ground, sniffing a lot of things, licking several things, and eating a few things.

Unfortunately, their curiosity sometimes gets them into trouble, especially if they nibble on mushrooms. Many mushrooms are toxic and can cause serious or even life-threatening illness. Here are a few things you need to know about mushroom toxicity.

Where do toxic mushrooms grow?

Mushrooms grow best in warm, wet weather and flourish in many places in Canada and the United States. They grow in wooded areas, rocky terrains, grassy parks, and even in your own backyard. In warmer climates, they may grow year-round, but in most areas, spring and early fall are the prime growing seasons.

What do toxic mushrooms look like?

Some mushrooms look like umbrellas, as depicted in children’s books. Others look entirely different. There are many different species of mushrooms with a variety of characteristics, which makes identification of individual types quite complicated. If you aren’t a “mushroom expert”, it’s best to assume that any mushroom you find could be a poisonous one. It’s not necessary to know the name of every single mushroom species if you avoid them all.

How serious is mushroom poisoning?

The severity of mushroom-induced illness depends on the type and number of mushrooms ingested. Sometimes a pet may have mild gastrointestinal upset, including vomiting and/or diarrhea, which resolves at home. Other times, a pet becomes extremely sick and requires hospitalization. Unfortunately, some pets die despite therapy.

What does mushroom toxicity look like?

Just as there are many types of mushrooms, there are many types of toxic reactions to mushrooms. Signs vary with the mushroom species and amount of mushroom ingested by the pet. The toxins can be broken down into four general categories.

1. Gastrointestinal (GI) toxins. There are many mushroom varieties that cause an upset stomach. Pets may become ill within 15 minutes of nibbling on these mushrooms or symptoms may be delayed for up to 6 hours. The muscarinic mushroom is a noted variety that causes vomiting and diarrhea. Pets may become weak and dehydrated. Out-patient treatment may suffice, but hospitalization is often required to stop vomiting and diarrhea and restore fluid balance. These mushrooms can also cause a slow heart rate (bradycardia) and respiratory problems.

2. Hepatotoxic. These mushrooms affect the liver. With names like death cap or death angel, Amanita mushrooms sound really ominous, and they are. Amanita mushrooms cause liver failure, which can be deadly. Owners may see their dog or cat nibble this type of mushroom, but do not become concerned because their pet looks fine immediately afterward. Then 6–24 hours later, GI symptoms occur.

Some pets appear to get better for a while, but the underlying liver failure progresses. The pet becomes jaundiced, weak, lethargic, and sometimes comatose. What starts as mild GI upset quickly progresses to full-blown liver failure that can result in death in a matter of days. If not treated quickly and aggressively, liver failure is irreversible.

3. Nephrotoxic. Mushrooms in this category affect the kidneys. Symptoms include nausea, vomiting, inappetence, increased drinking and urination, and dehydration. Fortunately, these mushrooms are not plentiful in North America, so cases of toxicity in pets are rare. When illness does occur, signs can be delayed for 12 hours, up to a week or longer, so by the time treatment is sought, the damage is done.

4. Neurotoxic. Three main groups of mushrooms cause neurological signs: hydrazines, isoxazole, and psilocybin (hallucinogenic or “magic”) mushrooms. The onset of illness is fast, with signs occurring in 30 minutes, up to 6 hours. 

"Neurotoxic mushrooms can be found growing naturally in the Pacific northwest."

Signs include weakness, lack of coordination, tremors, hallucinations, vocalizations, disorientation, agitation, altered mentation, drooling, vomiting and seizures. Body temperature may rise. These toxins can also affect the kidneys and liver, causing a myriad of problems.

Unlike other cases of mushroom toxicity in pets, the source is often inside rather than outside. Pets are curious and may find their owner’s private stash of hallucinogenic mushrooms, which are especially appetizing if mixed with chocolate or other substances for flavoring. Neurotoxic mushrooms can be found growing naturally in the Pacific northwest.

How is mushroom poisoning diagnosed?

Evidence of exposure to mushrooms is the first factor in an accurate diagnosis. Tell your veterinarian if you suspect that your pet ate mushrooms and when it may have occurred. Be specific when describing symptoms and their time of onset. This information is vital for accurate diagnosis and prompt treatment.

After taking a thorough history, your veterinarian will perform a complete physical exam. Next, they will take blood and urine samples to determine organ function. A sample of stomach contents may also be retrieved to help identify the mushroom ingested. Since some mushroom toxins have a delayed effect on organs, liver and kidney function tests may be repeated every 24–48 hours to monitor function.

To help with identification, bring a mushroom specimen with you to the emergency hospital. Wrap the mushroom in a damp paper towel rather than a plastic bag: this will preserve the integrity of the specimen and make identification easier. You can also take a picture of the mushroom, but make sure to capture all aspects, including the gills, cap, stem, and surrounding area.

What is the treatment for mushroom poisoning?

As with most cases of poisoning, prompt treatment is critical to a successful outcome. Minimizing absorption of the toxin is critical, so identifying the mushroom in question may have to wait. Once your pet is stable, mushrooms can be identified by a mycologist at a local college or by visiting the North American Mycological Association website.

There are several ways to decrease the amount of toxin that enters the bloodstream. If your pet sees your veterinarian soon after ingestion, the veterinarian may induce vomiting to remove mushrooms from the stomach. A GI medication called activated charcoal can be administered that will bind with the toxin and prevent its absorption. Sometimes, the doctor may perform a gastric lavage to eliminate any remaining mushrooms from the stomach.

Your pet will also be given intravenous (IV) fluids to combat dehydration and flush toxins from the body. Fluids also support kidney and liver function while toxins that have already been absorbed are processed.

For neurotoxic mushrooms, cyproheptadine is a medication that can reduce some of the neurological side effects. If your pet is experiencing seizures, then medications such as diazepam can be administered.

How can I prevent mushroom poisoning?

First, assume that all mushrooms growing in the wild are harmful until proven otherwise. If your pet wanders outside unsupervised, remove all mushrooms in your yard. Patrol the yard regularly — mushrooms spring up quickly! If you have trouble eliminating all the mushrooms from your yard, consult an expert.

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